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Malcolm D Mason Selected Research

hammerhead ribozyme

1/2017Potential Implication of Paxillin in Cancer Establishment Within the Bone Environment.
3/2016Targeting of Receptor Activator of Nuclear Kappa B (RANK) in PC-3 Cells Increases Cell Proliferation and Matrix Adhesion In Vitro.
7/2008Phospholipase-C gamma-1 (PLCgamma-1) is critical in hepatocyte growth factor induced in vitro invasion and migration without affecting the growth of prostate cancer cells.
10/2007Suppression of hepatocyte growth factor activator inhibitor-1 leads to a more aggressive phenotype of prostate cancer cells in vitro.
8/2005Targeting matrilysin and its impact on tumor growth in vivo: the potential implications in breast cancer therapy.
9/2004Targeting the HGF/SF receptor c-met using a hammerhead ribozyme transgene reduces in vitro invasion and migration in prostate cancer cells.

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Malcolm D Mason Research Topics

Disease

80Prostatic Neoplasms (Prostate Cancer)
01/2022 - 01/2002
48Neoplasms (Cancer)
04/2022 - 01/2002
22Neoplasm Metastasis (Metastasis)
01/2022 - 01/2002
14Breast Neoplasms (Breast Cancer)
10/2018 - 08/2005
5Urinary Bladder Neoplasms (Bladder Cancer)
02/2012 - 06/2005
4Disease Progression
01/2022 - 07/2011
4Carcinoma (Carcinomatosis)
07/2011 - 06/2005
2Fatigue
10/2018 - 01/2013
2Lung Neoplasms (Lung Cancer)
08/2015 - 03/2015
2Colorectal Neoplasms (Colorectal Cancer)
09/2014 - 11/2013
2Melanoma (Melanoma, Malignant)
10/2013 - 04/2011
2Inflammation (Inflammations)
01/2013 - 06/2004
2Carcinoma in Situ
02/2012 - 06/2005
2Carcinogenesis
12/2010 - 06/2007
2Pain (Aches)
10/2006 - 06/2005
1Adenocarcinoma
01/2022
1Hypertension (High Blood Pressure)
01/2022
1Sudden Death
01/2022
1Septic Shock (Toxic Shock Syndrome)
01/2022
1Cardiovascular Diseases (Cardiovascular Disease)
01/2017
1Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2017
1Wounds and Injuries (Trauma)
01/2017
1Urinary Incontinence
12/2016
1Multiple Endocrine Neoplasia Type 2a (MEN 2)
03/2016
1Sepsis (Septicemia)
12/2015
1Precancerous Conditions
09/2015
1Vomiting
09/2015
1Nausea
09/2015

Drug/Important Bio-Agent (IBA)

23Hormones (Hormone)IBA
01/2022 - 09/2003
18Proteins (Proteins, Gene)FDA Link
04/2016 - 08/2005
11Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
01/2017 - 10/2005
10AndrogensIBA
01/2022 - 03/2006
9Docetaxel (Taxotere)FDA Link
12/2018 - 08/2005
8Biological ProductsIBA
03/2015 - 03/2008
7Prostate-Specific Antigen (Semenogelase)IBA
01/2022 - 10/2006
7Peptide Hydrolases (Proteases)FDA Link
03/2013 - 04/2006
6Pharmaceutical PreparationsIBA
05/2017 - 02/2012
6hammerhead ribozymeIBA
01/2017 - 09/2004
6Catalytic RNA (Ribozymes)IBA
06/2014 - 09/2004
5Abiraterone AcetateIBA
01/2022 - 08/2011
5abirateroneIBA
01/2022 - 11/2014
5Zoledronic Acid (Zometa)FDA Link
05/2017 - 03/2006
5Diphosphonates (Bisphosphonates)IBA
02/2016 - 09/2003
5yangzheng xiaojiIBA
09/2015 - 11/2012
5CytokinesIBA
08/2015 - 08/2005
5AntigensIBA
06/2015 - 08/2005
5Messenger RNA (mRNA)IBA
09/2014 - 08/2005
5TransglutaminasesIBA
10/2013 - 01/2007
5Serine Proteases (Serine Protease)IBA
03/2013 - 06/2007
5matriptase 2IBA
03/2013 - 06/2007
4Biomarkers (Surrogate Marker)IBA
11/2020 - 04/2014
4Peptides (Polypeptides)IBA
10/2014 - 08/2005
3Prednisolone (Predate)FDA LinkGeneric
01/2022 - 01/2017
3Celecoxib (Celebrex)FDA Link
05/2017 - 02/2009
3PaxillinIBA
01/2017 - 09/2008
3Neoplasm Antigens (Tumor Antigens)IBA
06/2015 - 07/2010
3Protein Tyrosine PhosphatasesIBA
11/2013 - 01/2012
3Clodronic Acid (Clodronate)IBA
09/2009 - 09/2003
2enzalutamideIBA
01/2022 - 11/2014
2RANK LigandIBA
03/2016 - 01/2013
2Matrix Metalloproteinases (MMPs)IBA
09/2014 - 04/2006
2human KISS1 proteinIBA
09/2014 - 10/2013
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
09/2014 - 06/2008
2Sucrose (Saccharose)IBA
04/2014 - 06/2010
2IntegrinsIBA
04/2014 - 06/2004
2GemcitabineFDA Link
02/2012 - 07/2011
2Prednisone (Sone)FDA LinkGeneric
10/2006 - 08/2005
1ElementsIBA
04/2022
1Acetates (Acetic Acid Esters)FDA Link
01/2022
1antiarrhythmic peptide (AAP)IBA
01/2022
1Alanine (L-Alanine)FDA Link
01/2022
1ParaffinIBA
11/2020
1DNA (Deoxyribonucleic Acid)IBA
11/2020
1Formaldehyde (Formol)FDA Link
11/2020
1Activated-Leukocyte Cell Adhesion Molecule (Neurolin)IBA
10/2019
1Interleukin-6 Receptors (Interleukin 6 Receptor)IBA
10/2018
1Interleukin-6 (Interleukin 6)IBA
10/2018
1DenosumabFDA Link
01/2017
1Testosterone (Sustanon)FDA Link
01/2017
14-amino-4'-hydroxylaminodiphenylsulfone (HADS)IBA
12/2016
1cabazitaxelFDA Link
12/2015
1Granulocyte Colony-Stimulating Factor (G-CSF)IBA
12/2015
1Capsules (Microcapsules)IBA
09/2015
1Angiogenesis Inducing Agents (Angiogenesis Factor)IBA
08/2015
1Epidermal Growth Factor (EGF)IBA
08/2015
15- ((2,6- dichlorobenzyl)sulfonyl)- 3- ((3,5- dimethyl- 4- ((2- (pyrrolidin- 1- ylmethyl)pyrrolidin- 1- yl)carbonyl)- 1H- pyrrol- 2- yl)methylene)- 1,3- dihydro- 2H- indol- 2- oneIBA
08/2015
1((3Z)- N- (3- chlorophenyl)- 3- ((3,5- dimethyl- 4- ((4- methylpiperazin- 1- yl)carbonyl)- 1H- pyrrol- 2- yl)methylene)- N- methyl- 2- oxo- 2,3- dihydro- 1H- indole- 5- sulfonamide)IBA
08/2015
1Proto-Oncogene Proteins c-metIBA
08/2015
1HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA
06/2015

Therapy/Procedure

40Therapeutics
01/2022 - 09/2003
26Radiotherapy
01/2022 - 01/2007
7Drug Therapy (Chemotherapy)
12/2018 - 08/2005
6Prostatectomy (Retropubic Prostatectomy)
10/2017 - 01/2007
4Castration
01/2021 - 08/2011
4Immunotherapy
08/2012 - 08/2005
3Aftercare (After-Treatment)
01/2019 - 12/2017
3Chinese Traditional Medicine (Traditional Chinese Medicine)
09/2015 - 03/2015
1Brachytherapy
12/2017
1Lymph Node Excision (Lymph Node Dissection)
01/2017
1Conformal Radiotherapy
12/2016